JACS에 발표된 Click chemistry를 이용한 킬레이션가능한 리간드에 대한 논문입니다.
“Click to Chelate”: Synthesis and Installation of Metal Chelates into
Biomolecules in a Single Step
Click chemistry has been employed for the assembly of novel and efficient triazole-based multidentate chelating systems while simultaneously attaching them to molecules of biological interest. The "click-to-chelate" approach offers a powerful new tool for the modification of (bio)molecules with metal chelators for potential diagnostic and therapeutic applications.